Prostaglandin Receptor Control

Prostaglandin Receptor Controls (43):

Cat. No.	Product Name	Effect	Purity

HY-19518

Latanoprostene bunod	Control	99.85%
Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) .

HY-B0600

Tafluprost	Control	99.47%
Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn²⁺-mTORpathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma.

HY-113331

Thromboxane B2	Control	99.00%
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation.

HY-105005

Crisdesalazine	Control	98.10%
Crisdesalazine (AAD-2004) is an anti-inflammatory agent that simultaneously blocks inflammation mediated by free radicals and prostaglandin E2 (PGE2). Crisdesalazine (AAD-2004) can be used to study neurodegeneration in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

HY-131696

11-deoxy Prostaglandin F1α	Control
11-deoxy Prostaglandin F1α (11-deoxy PGF1α) is an analog of prostaglandin F1α, exhibits side effects on intestines and causes the uterine contraction. 11-deoxy Prostaglandin F1α exhibits activity as vasopressor and bronchoconstrictor.

HY-120955

(+)-5-trans Cloprostenol	Control
Cloprostol, a synthetic derivative of prostaglandin F2α, is used as an ossified in veterinary medicine and the research of reproductive disorders in cattle, pigs and horses. (+)-5-trans Cloprostenol is a secondary impurity produced during the synthesis of (+) -cloprostenol.

HY-113756

trans-Latanoprost acid	Control
trans-Latanoprost acid is an isomer of Latanoprost acid. trans-Latanoprost acid may have the activity of reducing intraocular pressure. trans-Latanoprost acid is mainly prepared as an analytical standard for impurity detection and quantification.

HY-137288

17-Phenyl-18,19,20-trinor-PGD2	Control
17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988). 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC₅₀ of 8.4 μM (PGD2 IC₅₀ = 18.6 nM). 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation.

HY-137133

Prostaglandin E1 alcohol	Control
Prostaglandin E1 alcohol (compound 89) is a prostaglandin analog.

HY-121825

U-44069	Control
U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels.

HY-129638

L-10503	Control
L-10503 is a non-hormonal non-prostaglandin antifertility compound.

HY-111271B

(R)-L 888607	Control	99.69%
(R)-L 888607 is the isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a K_i value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite.

HY-137119A

8,12-iso-iPF2α-VI	Control
8,12-iso-iPF2α-VI is a F2-isoprostanes. 8,12-iso-iPF2α-VI is a sensitive and specific marker of in vivo lipid peroxidation. 8,12-iso-iPF2α-VI can be used as a biomarker of oxidative damage in alzheimer's disease.

HY-114892

15-A2t-Isoprostane	Control
15-A2t-Isoprostane (8-iso Prostaglandin A2) is an isoprostaglandin produced by the non-enzymatic oxidation of arachidonic acid.

HY-132277

15-Keto Bimatoprost	Control
15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive.

HY-118465

ent-Prostaglandin E2	Control
ent-Prostaglandin E2 (ent-PGE2) is an enantiomer of PGE2 (HY-101952). unlike PGE2, ent-PGE2 is a poor substrate for 15-hydroxyprostaglandin dehydrogenase.

HY-114961

15-epi Prostaglandin A1	Control
15-epi Prostaglandin A1 (15-epi PGA1) is the 15(R) stereoisomer of PGA1. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive models.

HY-137908

11β-Misoprostol	Control
11β-Misoprostol is one of several impurities which are possible in the production of Misoprostol. Misoprostol is a 15-deoxy-l6-hydroxy-l6-methyl analog of prostaglandin El (PGE1).

HY-114867

(15R)-Bimatoprost	Control
(15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide) is a prostaglandin analog used to treat glaucoma and ocular hypertension. (15R)-Bimatoprost is an isomer of Bimatoprost with an inverted (β) hydroxyl group on C-15.

HY-118294

15-OH Tafluprost	Control
15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments.

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